The purpose of this executive order is to use artificial intelligence to develop solutions and cures for pediatric cancer. The initial focus shall be on identifying opportunities to accelerate the progress of AI driven solutions at the Childhood Cancer Data Initiative (CCDI) by consolidating data from multiple sources for AI analysis and analyzing complex biologic systems to improve predictive modeling of patient response, disease, progression and treatment toxicity. The MAHA Commission is directed to identify and implement strategies for increasing investment from existing federal funds for the CCDI and to encourage the private sector to make use of the most advanced technologies to unlock cures for pediatric cancer, including those based on AI.